General Information

  • ID:  hor003616
  • Uniprot ID:  P84379
  • Protein name:  Periviscerokinin-21
  • Gene name:  NA
  • Organism:  Deropeltis cf. erythrocephala JT-2004 (Cockroach)
  • Family:  Periviscerokinin family
  • Source:  animal
  • Expression:  Abdominal perisympathetic organs.
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Deropeltis (genus), Blattinae (subfamily), Blattidae (family), Blattoidea (superfamily), Blattodea (order), Dictyoptera (superorder), Polyneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  GGSSGLISMPRV
  • Length:  12
  • Propeptide:  GGSSGLISMPRV
  • Signal peptide:  NA
  • Modification:  T12 Valine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic activity
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003616_AF2.pdbhor003616_ESM.pdb

Physical Information

Mass: 135673 Formula: C48H85N15O16S
Absent amino acids: ACDEFHKNQTWY Common amino acids: GS
pI: 10.55 Basic residues: 1
Polar residues: 6 Hydrophobic residues: 3
Hydrophobicity: 39.17 Boman Index: -607
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 89.17
Instability Index: 6583.33 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  15626499
  • Title:  A proteomic approach for studying insect phylogeny: CAPA peptides of ancient insect taxa (Dictyoptera, Blattoptera) as a test case.